The ESEP study: Salpingostomy versus salpingectomy for tubal ectopic pregnancy; The impact on future fertility: A randomised controlled trial
2008

Comparing Salpingostomy and Salpingectomy for Ectopic Pregnancy

Sample size: 450 publication Evidence: moderate

Author Information

Author(s): Femke Mol, Annika Strandell, Davor Jurkovic, Tamer Yalcinkaya, Harold R Verhoeve, Carolien AM Koks, Paul JQ van der Linden, Giuseppe CM Graziosi, Andreas L Thurkow, Annemieke Hoek, Lars Hogström, Ingemar Klinte, Kerstin Nilsson, Norah M van Mello, Willem M Ankum, Fulco van der Veen, Ben WM Mol, Petra J Hajenius

Primary Institution: Academic Medical Centre, University of Amsterdam

Hypothesis

Does salpingostomy provide a better fertility prognosis compared to salpingectomy in women with tubal ectopic pregnancy?

Conclusion

The study aims to determine if the benefits of salpingostomy outweigh its risks compared to salpingectomy.

Supporting Evidence

  • Salpingostomy preserves the fallopian tube but carries risks of persistent trophoblast and repeat ectopic pregnancy.
  • Salpingectomy avoids these risks but leaves only one tube for future pregnancies.
  • The study will assess fertility outcomes up to 36 months post-surgery.

Takeaway

This study is trying to find out if a surgery that saves the fallopian tube helps women get pregnant better than a surgery that removes it.

Methodology

An international multi-centre randomised controlled trial comparing salpingostomy versus salpingectomy in women with tubal ectopic pregnancy.

Potential Biases

Potential biases may arise from the selection of participants and the randomization process.

Limitations

The study may have limitations related to the generalizability of results due to the specific inclusion criteria.

Participant Demographics

Women aged 18 and older with a presumptive diagnosis of tubal ectopic pregnancy.

Digital Object Identifier (DOI)

10.1186/1472-6874-8-11

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