Non-alcoholic beverages and bladder cancer risk in Uruguay
Author Information
Author(s): De Stefani Eduardo, Boffetta Paolo, Deneo-Pellegrini Hugo, Correa Pelayo, Ronco Alvaro L, Brennan Paul, Ferro Gilles, Acosta Giselle, Mendilaharsu María
Primary Institution: Grupo de Epidemiología, Departamento de Anatomía Patológica, Hospital de Clínicas, Facultad de Medicina, Montevideo, Uruguay
Hypothesis
Is there a link between the consumption of non-alcoholic beverages and the risk of bladder cancer in Uruguay?
Conclusion
Drinking maté, coffee, and tea may increase the risk of bladder cancer in Uruguay.
Supporting Evidence
- Ever maté drinking was positively associated with bladder cancer with an odds ratio of 2.2.
- Coffee drinking had an odds ratio of 1.6 for bladder cancer risk.
- Tea drinking was associated with an odds ratio of 2.3 for bladder cancer risk.
- The risk increased with the amount and duration of maté drinking.
- Results were confirmed in a separate analysis of never-smokers.
Takeaway
Drinking certain hot drinks like maté, coffee, and tea might make you more likely to get bladder cancer.
Methodology
A case-control study with 255 bladder cancer cases and 501 controls matched by age, sex, and residence, using face-to-face interviews.
Potential Biases
Possible residual confounding by tobacco smoking.
Limitations
Selection bias and misclassification bias are potential issues; the sample size may limit the power to detect interactions.
Participant Demographics
Most participants were male (225 cases), with a higher proportion of cases living outside Montevideo.
Statistical Information
P-Value
<0.01
Confidence Interval
95% CI 1.2–3.9 for maté drinking
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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