Amorphous calcium phosphate and its application in dentistry
2011

Amorphous Calcium Phosphate and Its Application in Dentistry

publication Evidence: moderate

Author Information

Author(s): Zhao Jie, Liu Yu, Sun Wei-bin, Zhang Hai

Primary Institution: Stomatological Hospital, Nanjing University Medical School

Conclusion

Amorphous calcium phosphate (ACP) is a promising material for dental applications due to its excellent biocompatibility and ability to promote remineralization.

Supporting Evidence

  • ACP has better osteoconductivity and biodegradability than tricalcium phosphate and hydroxyapatite.
  • ACP can increase alkaline phosphatase activities of mesoblasts and enhance cell proliferation.
  • ACP-filled bioactive composites are effective anti-demineralizing/remineralizing agents for tooth structures.

Takeaway

Amorphous calcium phosphate is a special type of calcium phosphate that helps repair teeth and bones by turning into a stronger form when needed.

Methodology

This review summarizes the development, structure, and biomedical applications of ACP in dentistry.

Limitations

The review does not provide new experimental data but summarizes existing literature.

Digital Object Identifier (DOI)

10.1186/1752-153X-5-40

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