Lipids, Lipoproteins, and Age-Related Macular Degeneration
2011
Lipids, Lipoproteins, and Age-Related Macular Degeneration
publication
Evidence: moderate
Author Information
Author(s): Ebrahimi Katayoon B., Handa James T.
Primary Institution: Wilmer Eye Institute, Johns Hopkins School of Medicine
Hypothesis
How do systemic and local production of lipoproteins contribute to the pathogenesis of age-related macular degeneration (AMD)?
Conclusion
The study suggests that lipoproteins accumulate in Bruch's membrane and may play a significant role in the development of AMD.
Supporting Evidence
- Age-related macular degeneration (AMD) is the leading cause of blindness among the elderly.
- 1.75 million people are affected by advanced AMD in the U.S.
- The financial impact of AMD is estimated to be $2.6 billion in Canada and Australia.
Takeaway
This study looks at how fats in the body might cause eye problems in older people, especially those that can lead to blindness.
Digital Object Identifier (DOI)
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