ARE STATINS THAT GOOD? ASSESSING THE PROTECTIVE EFFECT OF STATINS AMONG OLDER ADULTS WITH SERIOUS ILLNESS OR INJURY
2024

The Protective Effects of Statins in Older Adults

Sample size: 1771 publication Evidence: moderate

Author Information

Author(s): Sanchez-Reilly Sandra, Yarrarapu Siva Naga Srinivas, Sidle Erin, Khalikov Marla, LaCoss Jennifer, Reilly Elizabeth, Crenshaw Shannon, McGinity Ashley

Primary Institution: South Texas Veterans Health Care System and the University of Texas Health Science Center at San Antonio

Hypothesis

Do statins provide protective effects among older adults with serious illness or injury?

Conclusion

Statins appear to significantly reduce fall risk and in-hospital mortality among older adults.

Supporting Evidence

  • 50% of older adults in the study were using statins.
  • 25% of emergency visits were due to falls.
  • Statin-takers had a lower in-hospital mortality rate compared to non-statin users.

Takeaway

This study found that older adults who take statins are less likely to fall and die from injuries compared to those who don't take them.

Methodology

Data on older adult emergency department visits were collected over seven weeks, focusing on acuity scores, diagnoses, ICU admissions, deaths, and statin usage.

Potential Biases

Potential biases in self-reported statin usage and confounding variables.

Limitations

The study is observational and may not account for all confounding factors.

Participant Demographics

Median age 73, 52% female, 34% White, 55% Hispanic.

Statistical Information

P-Value

p=0.04

Statistical Significance

p=0.002

Digital Object Identifier (DOI)

10.1093/geroni/igae098.3791

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