Immunohistochemical Features of a Rare Endometrial Cancer
Author Information
Author(s): Ribeiro-Silva Alfredo
Primary Institution: Department of Pathology, Ribeirão Preto Medical School, University of São Paulo, Brazil
Hypothesis
What are the immunohistochemical features of papillary squamous cell carcinoma of the endometrium with transitional cell differentiation?
Conclusion
The study found that the tumor expressed several markers suggesting anti-apoptotic stimuli are significant in this rare neoplasm.
Supporting Evidence
- The tumor was diagnosed as papillary squamous cell carcinoma with transitional cell differentiation.
- The patient recovered well after surgery but died one year later due to disseminated disease.
- Immunohistochemical staining showed positivity for several markers including p63 and bcl-2.
Takeaway
This study looks at a rare type of endometrial cancer in an 84-year-old woman and how certain markers in the tumor might affect its behavior.
Methodology
An immunohistochemical panel with 32 markers was performed on the tumor.
Limitations
The findings are based on a single case, and further studies with larger patient series are needed.
Participant Demographics
An 84-year-old woman, gravida 7 para 4, postmenopausal.
Digital Object Identifier (DOI)
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