Screening for Type 2 Diabetes in Asian Indians
Author Information
Author(s): Mohan V., Goldhaber-Fiebert Jeremy D., Radha V., Gokulakrishnan K.
Primary Institution: Madras Diabetes Research Foundation & Dr Mohan’s Diabetes Specialities Centre
Hypothesis
Is screening for undiagnosed type 2 diabetes more effective and cost-efficient using the Indian Diabetes Risk Score compared to traditional methods?
Conclusion
Using the Indian Diabetes Risk Score is more effective and less expensive for screening undiagnosed type 2 diabetes than genotyping or universal oral glucose tolerance testing.
Supporting Evidence
- OGTT identified 72 subjects with newly diagnosed diabetes.
- IDRS screening yielded 413 positive subjects, including 54 of the 72 NDD subjects identified by OGTT.
- Genotyping identified only 36 of the 72 NDD subjects, showing less discriminatory power.
Takeaway
This study shows that a simple score can help find people with diabetes without needing expensive tests.
Methodology
The study involved screening 961 subjects without known diabetes using OGTT, IDRS, and genotyping for TCF7L2 polymorphisms.
Limitations
The study does not measure long-term costs associated with diabetes management and does not include travel costs for screening.
Participant Demographics
Participants were Asian Indians aged over 20 years from Chennai.
Statistical Information
P-Value
p<0.001
Statistical Significance
p<0.001
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