Whence Feral Vaccinia?
2010

Understanding Feral Vaccinia

Sample size: 344 Commentary Evidence: moderate

Author Information

Author(s): Richard C. Condit

Primary Institution: University of Florida

Conclusion

There is a surprisingly high incidence of vaccinia infection in the Brazilian wilderness, particularly among monkeys.

Supporting Evidence

  • 24% of the animals tested were seropositive for orthopoxvirus.
  • 18 serum samples tested positive for orthopoxvirus DNA.
  • Sequencing revealed the vaccinia strain associated with outbreaks in Brazil.

Takeaway

Scientists found that many monkeys in Brazil have a virus related to the smallpox vaccine, which is surprising because we didn't think monkeys could carry it.

Methodology

A serosurvey was conducted among 344 wild animals, including 296 monkeys, to test for orthopoxvirus.

Limitations

The study does not identify monkeys as a primary reservoir for the virus or address how the virus is transmitted among these animals.

Participant Demographics

The study involved 344 wild animals from the Brazilian Amazon, predominantly monkeys.

Digital Object Identifier (DOI)

10.3201/eid1606.100315

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