Survival and Histopathological Study of Animals Bearing Ehrlich Tumor Treated with a Rhodium(II) Amidate
1999

Survival Study of Tumor-Bearing Mice Treated with Rhodium(II) Amidate

Sample size: 14 publication Evidence: moderate

Author Information

Author(s): Breno Pannia EspSsito, Szulim Ber Zyngier, Renato Najjar, Roberto Pinto Paes, Suely M. Ykko Ueda, Jos6 Carlos A. Barros

Primary Institution: University of São Paulo

Hypothesis

The study investigates the survival rate of tumor-bearing mice treated with a specific rhodium(II) complex.

Conclusion

The treatment with the rhodium(II) complex allowed for a 90% survival rate in tumor-bearing mice.

Supporting Evidence

  • The survival rate of 90% was achieved with the rhodium(II) complex.
  • Histopathological alterations were observed in various tissues of treated mice.
  • The Survgo dose was determined to be 3.8x10.5 mol/kg.

Takeaway

Researchers gave a special medicine to sick mice and found that most of them lived longer.

Methodology

The study involved treating Balb-c mice with a rhodium(II) complex and assessing survival and histopathological changes.

Limitations

The study only included a small number of mice and focused on specific histopathological alterations.

Participant Demographics

Male Balb-c mice were used in the study.

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