Liver transplantation for malignancy
1991

Liver Transplantation for Cancer

Editorial Evidence: low

Author Information

Author(s): N.J. London, G.R. Giles

Primary Institution: University Department of Surgery, St James's University Hospital

Conclusion

Liver transplantation for malignancy shows poor overall prognosis, but certain patients may benefit.

Supporting Evidence

  • Patients with small hepatocellular carcinomas have a 5-year survival rate of 63.2% after resection.
  • Only about one quarter of patients referred to transplant centers are suitable for liver transplantation.
  • The prognosis for patients with biliary tract tumors after liver transplantation is poor.
  • Accurate staging of tumors is vital before transplantation.

Takeaway

Doctors are trying to help people with liver cancer by replacing their liver, but it doesn't always work well. Some patients do better than others.

Limitations

The prognosis for liver transplantation in cancer patients is generally poor, and many factors affecting survival are not well understood.

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