Retrospective Audit of Transfusion Reactions in a Tertiary-Care Hospital in South India
2024

Audit of Blood Transfusion Reactions in South India

Sample size: 23028 publication Evidence: moderate

Author Information

Author(s): Muacevic Alexander, Adler John R, Priya Sabari, V Karthikeyan, Srinivasan Sowmya

Primary Institution: Mahatma Gandhi Medical College and Research Institute, Pondicherry, IND

Hypothesis

What is the frequency and type of transfusion reactions occurring among in-patients at our hospital?

Conclusion

The low incidence of transfusion reactions (0.5%) may be due to underreporting, highlighting the need for better education and documentation practices.

Supporting Evidence

  • Out of 23,028 units transfused, 105 cases of transfusion reactions were documented.
  • The most common reaction was febrile non-hemolytic transfusion reaction (59%).
  • The incidence of transfusion reactions was higher among males (50.5%) than females (49.5%).
  • The majority of reactions occurred in individuals with blood group B (38%).

Takeaway

This study looked at how often patients had bad reactions to blood transfusions, and found that it doesn't happen very often, but some reactions might not be reported.

Methodology

This was a cross-sectional study analyzing transfusion reactions reported to the blood center over three years and nine months.

Potential Biases

Potential underreporting of reactions due to lack of awareness among healthcare professionals.

Limitations

The study relied on reported reactions, which may have been underreported, especially mild reactions.

Participant Demographics

The study included in-patients at a tertiary-care hospital, with a higher incidence of reactions among males and individuals aged 41-50.

Digital Object Identifier (DOI)

10.7759/cureus.74930

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