Mast Cells and Basophils in Major Viral Diseases
Author Information
Author(s): Gammeri Luca, Sanfilippo Serena, Alessandrello Clara, Gangemi Sebastiano, Minciullo Paola Lucia
Primary Institution: Department of Clinical and Experimental Medicine, School and Operative Unit of Allergy and Clinical Immunology, University of Messina, Italy
Hypothesis
What are the correlations with SARS-CoV-2, Influenza A Viruses, HIV, and Dengue?
Conclusion
Mast cells and basophils play crucial roles in the pathogenesis of viral diseases, influencing both immune responses and disease severity.
Supporting Evidence
- Mast cells and basophils are involved in the immune response to SARS-CoV-2 and other viral infections.
- Changes in basophil and mast cell levels may indicate disease severity in COVID-19.
- Artificial intelligence could enhance diagnostic and prognostic tools related to viral infections.
Takeaway
Mast cells and basophils are important immune cells that help our body fight off viruses, but they can also cause problems if they react too strongly.
Methodology
A strategic search through PubMed was performed to find studies regarding the role of basophils and mast cells in various viral infections, resulting in the selection of 58 valuable articles.
Limitations
The review is limited to studies published in English and may not encompass all relevant research on the topic.
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website