Vaccination Efficacy in Myeloma Patients
Author Information
Author(s): Robertson J D, Nagesh K, Jowitt S N, Dougal M, Anderson H, Mutton K, Zambon M, Scarffe J H
Primary Institution: Christie Hospital NHS Trust
Hypothesis
How effective is vaccination against influenza and certain bacteria in patients with multiple myeloma?
Conclusion
The study found that routine vaccination against influenza and pneumococcal disease may not be effective in patients with multiple myeloma.
Supporting Evidence
- No patient had protective antibody titres to all three antigens prior to vaccination.
- Only 19% of patients achieved protective antibody titres post vaccination.
- 93% of patients had suboptimal antibody titres before vaccination.
Takeaway
This study looked at how well vaccines work for people with a type of cancer called multiple myeloma, and it found that the vaccines didn't work very well.
Methodology
Patients were vaccinated and their antibody levels were measured before and after vaccination.
Limitations
The study had a small sample size and focused only on specific vaccines.
Participant Demographics
Patients with multiple myeloma attending outpatient clinics.
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website