Ventilator associated pneumonia and transfusion, is there really an association? (the NAVTRA study)
2006

Association Between Transfusions and Ventilator Associated Pneumonia

Sample size: 474 publication Evidence: moderate

Author Information

Author(s): David Yepes, Gil Bladimir, Olga Hernandez, Rodrigo Murillo, Marco Gonzalez, Juan Pablo Velasquez

Primary Institution: Clinica Universitaria Bolivariana and Clinica CES, University CES, MedellĂ­n, Colombia

Hypothesis

Patients on mechanical ventilation who are transfused with packed red blood cells present an incidence of NAV equal to patients who are not transfused during the stay in ICU.

Conclusion

The study aims to establish the association between transfusions and ventilator associated pneumonia in ICU patients.

Supporting Evidence

  • Anemia is common in ICU patients and can lead to the need for transfusions.
  • Transfusions can have complications, including an increased risk of infections.
  • Ventilator associated pneumonia is a significant concern in ICU settings.

Takeaway

This study is trying to find out if giving blood transfusions to patients on ventilators makes them more likely to get pneumonia.

Methodology

This is a multicenter, prospective cohort study involving 474 patients on mechanical ventilation for more than 48 hours.

Participant Demographics

Patients in intensive care units in Colombia, aged 18 and older.

Statistical Information

P-Value

<0.05

Confidence Interval

95%

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1471-2466-6-18

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