Extensive production of Neospora caninum tissue cysts in a carnivorous marsupial succumbing to experimental neosporosis
2011

Neospora caninum in Fat-Tailed Dunnarts

Sample size: 15 publication 10 minutes Evidence: moderate

Author Information

Author(s): Jessica S King, Bronwyn McAllan, Derek S Spielman, Scott A Lindsay, Lada Hůrková-Hofmannová, Ashlie Hartigan, Sarwat E Al-Qassab, John T Ellis, Jan Šlapeta

Primary Institution: University of Sydney

Hypothesis

Can the fat-tailed dunnart serve as an intermediate host for Neospora caninum?

Conclusion

The fat-tailed dunnart is highly susceptible to Neospora caninum, producing numerous tissue cysts throughout its body.

Supporting Evidence

  • Dunnarts showed severe clinical signs after infection with Neospora caninum.
  • Histopathology revealed numerous N. caninum cysts in various tissues.
  • The study provides evidence for a sylvatic life cycle of N. caninum in Australia.

Takeaway

Researchers found that a small marsupial called the fat-tailed dunnart can get very sick from a parasite called Neospora caninum, which makes lots of cysts in its body.

Methodology

The study involved experimentally infecting fat-tailed dunnarts with Neospora caninum tachyzoites and monitoring their health and behavior.

Potential Biases

Potential bias due to the controlled laboratory environment and the specific conditions of the experiment.

Limitations

The study was limited to a small sample size and focused on a single species.

Participant Demographics

Fifteen adult male fat-tailed dunnarts aged 1-2 years.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1297-9716-42-75

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