Congenital Cytomegalovirus Infection and Neonatal Pulmonary Hypertension
Author Information
Author(s): Walter-Nicolet Elizabeth, Leblanc Magali, Leruez-Ville Marianne, Hubert Philippe, Mitanchez Delphine
Primary Institution: Hôpital Armand Trousseau, AP-HP, Faculté de Médecine, Université Pierre et Marie Curie, Paris, France
Hypothesis
Can congenital cytomegalovirus (CMV) infection lead to neonatal persistent pulmonary hypertension?
Conclusion
Congenital CMV infection can cause neonatal persistent pulmonary hypertension, requiring intensive respiratory support and antiviral therapy.
Supporting Evidence
- Congenital CMV infection is a common cause of neonatal morbidity.
- Both infants presented with severe hypoxemia and required intensive respiratory support.
- One infant died, while the other survived and developed normally at 15 months.
Takeaway
Some babies can get really sick from a virus called CMV, which can make it hard for them to breathe. Doctors can help them with special treatments.
Methodology
Case report of two infants with congenital CMV infection and persistent pulmonary hypertension, detailing their clinical management and outcomes.
Limitations
The study is based on only two cases, limiting the generalizability of the findings.
Participant Demographics
Two infants, one female and one male, born to mothers with different pregnancy histories.
Digital Object Identifier (DOI)
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