Congenital Cytomegalovirus Infection Manifesting as Neonatal Persistent Pulmonary Hypertension: Report of Two Cases
2011

Congenital Cytomegalovirus Infection and Neonatal Pulmonary Hypertension

Sample size: 2 publication Evidence: low

Author Information

Author(s): Walter-Nicolet Elizabeth, Leblanc Magali, Leruez-Ville Marianne, Hubert Philippe, Mitanchez Delphine

Primary Institution: Hôpital Armand Trousseau, AP-HP, Faculté de Médecine, Université Pierre et Marie Curie, Paris, France

Hypothesis

Can congenital cytomegalovirus (CMV) infection lead to neonatal persistent pulmonary hypertension?

Conclusion

Congenital CMV infection can cause neonatal persistent pulmonary hypertension, requiring intensive respiratory support and antiviral therapy.

Supporting Evidence

  • Congenital CMV infection is a common cause of neonatal morbidity.
  • Both infants presented with severe hypoxemia and required intensive respiratory support.
  • One infant died, while the other survived and developed normally at 15 months.

Takeaway

Some babies can get really sick from a virus called CMV, which can make it hard for them to breathe. Doctors can help them with special treatments.

Methodology

Case report of two infants with congenital CMV infection and persistent pulmonary hypertension, detailing their clinical management and outcomes.

Limitations

The study is based on only two cases, limiting the generalizability of the findings.

Participant Demographics

Two infants, one female and one male, born to mothers with different pregnancy histories.

Digital Object Identifier (DOI)

10.1155/2011/293285

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