An Evaluation of 90Y Bremsstrahlung SPECT Image Quality in the Presence of 99mTc: A Technical Perspective on Same-Day Radioembolization
2024

Evaluating Image Quality in Same-Day Radioembolization

publication Evidence: moderate

Author Information

Author(s): Keane Grace, van Rooij Rob, Lam Marnix, Braat Arthur, Smits Maarten, de Jong Hugo

Primary Institution: Department of Radiology and Nuclear Medicine, University Medical Center Utrecht

Hypothesis

This study aimed to quantify the impact of 99mTc on 90Y bremsstrahlung-SPECT/CT image quality and to establish an optimised imaging protocol.

Conclusion

The study found that advanced reconstruction techniques significantly improved post-treatment image quality in dual-isotope settings.

Supporting Evidence

  • Image quality degradation was noted in dual-isotope settings even when using an optimised protocol.
  • Advanced reconstruction techniques markedly improved post-treatment image quality.
  • The highest contrast recovery coefficients were achieved with an advanced Monte Carlo-based reconstruction.

Takeaway

This study looked at how a certain type of imaging can be affected when two different substances are used together, and it found ways to make the images clearer.

Methodology

The study used a NEMA IQ phantom to measure contrast recovery coefficients (CRCs) for different imaging protocols.

Limitations

The study used a phantom model that may not fully represent clinical scenarios, and the imaging protocol lacked background compensation.

Digital Object Identifier (DOI)

10.3390/curroncol31120554

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