The utility of tumour markers in assessing the response to chemotherapy in advanced bladder cancer
2000
Using Tumor Markers to Monitor Chemotherapy in Bladder Cancer
Sample size: 74
publication
Evidence: moderate
Author Information
Author(s): Cook A M, Huddart R A, Jay G, Norman A, Dearnaley D P, Horwich A
Primary Institution: The Royal Marsden NHS Trust and Institute of Cancer Research
Hypothesis
Can tumor markers effectively monitor the response to chemotherapy in patients with advanced bladder cancer?
Conclusion
Monitoring tumor markers can help predict how well patients with advanced bladder cancer respond to chemotherapy.
Supporting Evidence
- 58% of patients had at least one raised tumor marker.
- 49% of assessable patients had a radiological response.
- No patient had a clinical response without a marker response.
Takeaway
Doctors can check certain markers in the blood to see if chemotherapy is working for bladder cancer patients.
Methodology
Serum levels of tumor markers were measured in patients receiving chemotherapy.
Participant Demographics
Patients with advanced bladder cancer receiving chemotherapy.
Statistical Information
P-Value
p=0.0001
Statistical Significance
p=0.002
Digital Object Identifier (DOI)
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