Smoking and Peripheral Arterial Disease in Korean Men
Author Information
Author(s): Lee Young-Hoon, Shin Min-Ho, Kweon Sun-Seog, Choi Jin-Su, Rhee Jung-Ae, Ahn Hye-Ran, Yun Woo-Jun, Ryu So-Yeon, Kim Bok-Hee, Nam Hae-Sung, Jeong Seul-Ki, Park Kyeong-Soo
Primary Institution: Chonnam National University Hospital
Hypothesis
Is there an association between cumulative smoking exposure, duration of smoking cessation, and peripheral arterial disease (PAD) in middle-aged and older Korean men?
Conclusion
Cumulative smoking exposure and duration of smoking cessation were significantly associated with PAD in middle-aged and older Korean men.
Supporting Evidence
- The odds ratio for PAD was 2.31 for former smokers and 4.30 for current smokers compared to never smokers.
- There was a significant dose-response relationship between pack-years of smoking and PAD.
- The risk of PAD decreased significantly with longer duration of smoking cessation.
Takeaway
Smoking a lot can hurt your blood vessels, and if you stop smoking for a long time, it can help your blood vessels get better.
Methodology
The study analyzed 2517 community-dwelling Korean men aged 50 and older, assessing smoking habits and measuring PAD using the ankle-brachial index.
Potential Biases
Potential unmeasured confounding variables could affect the association between smoking and PAD.
Limitations
The cross-sectional design limits causal conclusions, and self-reported smoking data may introduce measurement errors.
Participant Demographics
Community-dwelling Korean men aged 50 years and older.
Statistical Information
P-Value
p<0.05
Confidence Interval
95% CI for ORs provided in results
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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