Effect of Tetrapropylammonium Chloride on PLA/PEG Electrospun Mat
Author Information
Author(s): Şener Sena Özdil, Samatya Yilmaz Sema, Doganci Merve Dandan, Doganci Erdinc
Primary Institution: Kocaeli University
Hypothesis
This study investigates the effect of tetrapropylammonium chloride (TCL) on the properties of PLA/PEG electrospun mats.
Conclusion
The addition of TCL salt improved the homogeneity and liquid absorption capacity of PLA/PEG nanofibers, making them suitable for wound dressing applications.
Supporting Evidence
- The addition of TCL salt reduced bead formation in PLA–PEG nanofibers.
- PLA–5TCL–PEG exhibited the highest liquid absorption capacity with a maximum increase of 150%.
- High cell viability was observed in L292 mouse fibroblast cells with the effect of TCL salt.
- PLA–TCL–PEG nonwoven webs showed no antibacterial activity against E. coli and S. aureus.
Takeaway
This study shows that adding a special salt to a type of plastic can make it better for healing wounds by helping it absorb liquids and be less bumpy.
Methodology
The study involved producing PLA–PEG nonwoven networks with varying concentrations of TCL and evaluating their properties through various tests including cytotoxicity and liquid absorption capacity.
Limitations
The study did not observe antibacterial activity in the PLA–TCL–PEG nonwoven webs.
Digital Object Identifier (DOI)
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