Mononucleotide repeats are asymmetrically distributed in fungal genes
2008
Distribution of Mononucleotide Repeats in Fungal Genes
Sample size: 47
publication
Evidence: moderate
Author Information
Author(s): Mark WJ van Passel, Leo H de Graaff
Primary Institution: Wageningen University
Hypothesis
Are mononucleotide repeats distributed asymmetrically within fungal genes?
Conclusion
Mononucleotide repeats are intragenically biased in numerous fungal genomes, similar to earlier studies on prokaryotes.
Supporting Evidence
- The study found a 5' bias of intragenic mononucleotide repeats in fungal gene repertoires.
- Species-specific differences in gene fractions containing large repeats were observed.
- Long transcripts showed a more prominent bias towards gene termini.
Takeaway
This study looked at how certain DNA patterns are found more at the beginning of genes in fungi, which might help them avoid problems when making proteins.
Methodology
The study analyzed transcript data from 47 fungal genomes, focusing on the distribution of mononucleotide repeats in coding sequences.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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