Structure of N-(3,5-Dimethoxyphenyl)benzamide
Author Information
Author(s): Li Hong-Lei, Cui Jiang-Tao
Primary Institution: Nanjing University
Hypothesis
The study investigates the structural properties of N-(3,5-Dimethoxyphenyl)benzamide as a potential anti-tumor reagent.
Conclusion
The crystal structure of N-(3,5-Dimethoxyphenyl)benzamide reveals a planar methoxyphenyl amide segment and centrosymmetric dimers formed through intermolecular interactions.
Supporting Evidence
- The methoxyphenyl amide segment of the molecule is almost planar.
- The two benzene rings are inclined at an angle of 76.66°.
- Intermolecular N—H⋯O interactions generate centrosymmetric dimers.
Takeaway
The researchers looked at how a specific chemical compound is structured, which could help in making medicines that fight tumors.
Methodology
The compound was synthesized by stirring benzoyl chloride with 3,5-dimethoxyaniline in dioxane, followed by crystallization.
Limitations
The crystal was relatively weakly diffracting, which may affect the accuracy of the structural data.
Digital Object Identifier (DOI)
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