Anopheles gambiae complex along The Gambia river, with particular reference to the molecular forms of An. gambiae s.s.
2008

Distribution of Anopheles gambiae along the Gambia River

Sample size: 4079 publication 10 minutes Evidence: high

Author Information

Author(s): Caputo Beniamino, Nwakanma Davis, Jawara Musa, Adiamoh Majidah, Dia Ibrahima, Konate Lassana, Petrarca Vincenzo, Conway David J, della Torre Alessandra

Primary Institution: Istituto Pasteur-Fondazione Cenci-Bolognetti, Università 'La Sapienza', Rome, Italy

Hypothesis

The geographic and temporal distribution of M and S molecular forms of Anopheles gambiae s.s. has not been investigated in detail.

Conclusion

The study supports a bionomic divergence between the M and S-forms and suggests higher-than-expected hybridization between the two forms in the western extreme of their distribution.

Supporting Evidence

  • Over 4,000 An. gambiae s.l. adult females were collected and identified.
  • M-form was mainly found in areas with water-retaining alluvial deposits.
  • S-form prevailed in rural savannah areas of Eastern Senegal.
  • Hybrids between M and S-forms were found at frequencies ranging from 0.6% to 7%.
  • Anopheles melas and An. arabiensis frequencies were generally lower in rainy season samples.

Takeaway

Scientists studied mosquitoes along the Gambia River and found that two types of malaria-carrying mosquitoes live in different areas, with some mixing together more than expected.

Methodology

Indoor-resting An. gambiae s.l. females were collected along a 400 km transect and identified by PCR-RFLP.

Potential Biases

Potential underestimation of An. melas and An. arabiensis due to their behavior.

Limitations

The study may be biased by the collection method, which focused on indoor-resting mosquitoes.

Participant Demographics

The study involved collections from various ecological zones along the Gambia River.

Statistical Information

P-Value

p<0.001

Confidence Interval

95% CI

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.1186/1475-2875-7-182

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