Multifocal invasive ductal breast cancer with osteoclast-like giant cells: a case report
2011

Case Report of Breast Cancer with Giant Cells

Sample size: 1 publication Evidence: low

Author Information

Author(s): Georg Richter, Christoph Uleer, Thomas Noesselt

Primary Institution: Institute of Pathology, Hameln, Germany

Hypothesis

This is the first case report of multifocal invasive carcinoma of the breast containing osteoclast-like giant cells.

Conclusion

This case report highlights the rarity of osteoclast-like giant cells in breast cancer and suggests their potential role in early carcinogenesis.

Supporting Evidence

  • Osteoclast-like giant cells are described in less than 2% of breast cancers.
  • The patient had three radiodense lesions detected during routine mammography.
  • The diagnosis was confirmed through ultrasound-guided core needle biopsy.

Takeaway

A 64-year-old woman had a rare type of breast cancer with unusual giant cells, which might be important for understanding how breast cancer develops.

Methodology

The patient underwent mammography, ultrasound, and biopsy to diagnose multifocal invasive breast cancer.

Limitations

The significance of the presence of osteoclast-like giant cells in breast cancer is uncertain.

Participant Demographics

64-year-old Caucasian woman with no known family history of breast cancer.

Digital Object Identifier (DOI)

10.1186/1752-1947-5-85

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