PDBalert: automatic, recurrent remote homology tracking and protein structure prediction
2008

PDBalert: A System for Protein Structure Prediction

publication Evidence: moderate

Author Information

Author(s): Agarwal Vatsal, Remmert Michael, Biegert Andreas, Söding Johannes

Primary Institution: Indian Institute of Technology, Roorkee

Conclusion

PDBalert will accelerate the information flow from the PDB database to all those who can profit from the newly released protein structures for predicting the 3D structure or function of their proteins of interest.

Supporting Evidence

  • PDBalert uses advanced remote homology detection methods to find protein templates.
  • It sends email alerts to users when new homologous structures are released.
  • The system is integrated into a user-friendly web interface.

Takeaway

PDBalert is a tool that helps scientists get alerts when new protein structures are available, making it easier for them to study proteins.

Methodology

PDBalert checks the PDB database weekly for homologous templates and notifies users via email when matches are found.

Limitations

Users need to upload sequences of single protein domains for better sensitivity, and the system may miss some useful templates due to naming differences.

Digital Object Identifier (DOI)

10.1186/1472-6807-8-51

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