Histological Features of Delayed Foreign Body Granuloma With Epithelioid Histiocyte Aggregation and Eosinophilic Reaction due to Hyaluronic Acid Injection
2024

Delayed Foreign Body Granuloma from Hyaluronic Acid Injection

Sample size: 1 publication Evidence: low

Author Information

Author(s): Nishimura Michiko, Sakamoto Shinnichi, Hoshino Miyako, Miyazaki Yuji, Yamamoto Junichiro, Sakashita Hideaki, Kusama Kaoru, Kikuchi Kentaro

Primary Institution: Meikai University School of Dentistry

Hypothesis

What are the histological features of delayed foreign body granuloma associated with hyaluronic acid injection?

Conclusion

The case illustrates a delayed foreign body granuloma with eosinophilic and histiocytic infiltration following hyaluronic acid injection.

Supporting Evidence

  • The patient had a history of hyaluronic acid injections one year prior to the presentation.
  • Histopathological examination revealed eosinophilic infiltration and multinucleated giant cells.
  • The granuloma formation was diagnosed based on characteristic histological features.

Takeaway

A woman had a lump in her cheek after getting a cosmetic injection, and doctors found that her body reacted to the filler by creating a lump filled with special cells.

Methodology

The study involved a case presentation and histopathological examination of a biopsy specimen.

Limitations

The study is based on a single case report, limiting the generalizability of the findings.

Participant Demographics

A 61-year-old Japanese female patient.

Digital Object Identifier (DOI)

10.1155/crid/5565324

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