Clinical Outcomes of Curettage versus Surgical Resection of Giant Cell Tumor of the Distal Radius – A Systematic Review and Meta-analysis
2024

Comparing Treatments for Giant Cell Tumor of the Distal Radius

Sample size: 222 publication 10 minutes Evidence: moderate

Author Information

Author(s): Ali Sheikh Muhammad Ebad, Fatima Syeda Safeena, Munawar Bisma, Fatima Maheen, Naqvi Syeda Kisa Batool, Malik Laiba Urooj

Primary Institution: Mamji Hospital, Karachi, Pakistan

Hypothesis

Is there a difference in functional outcomes, complications, and recurrence rates between curettage and surgical resection for giant cell tumors of the distal radius?

Conclusion

Resection and reconstruction are preferred for treating giant cell tumors of the distal radius due to similar functional outcomes and lower recurrence rates compared to curettage.

Supporting Evidence

  • Seven studies were included, with a total of 222 subjects.
  • Patients in the curettage group had a higher recurrence rate.
  • Incidences of complications were similar in both groups.
  • Functional outcomes were also similar between the two surgical methods.

Takeaway

Doctors are trying to figure out the best way to treat a type of bone tumor in the wrist. They found that one method might be better at preventing the tumor from coming back.

Methodology

A systematic review and meta-analysis of studies comparing curettage and surgical resection for giant cell tumors of the distal radius.

Potential Biases

Potential bias due to the lack of randomization and exclusion of certain studies.

Limitations

No randomized controlled trials were found, and the grey literature was not searched.

Participant Demographics

222 participants, 117 males and 105 females, mean age 22.08 years.

Statistical Information

P-Value

p=0.015

Confidence Interval

95%CI=0.057–0.735

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1055/s-00042410

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