Helicobacter pylori and Iron Deficiency Anemia in Children
Author Information
Author(s): Hoseinzadeh Morteza, Khosravi Afra, Sayemiri Koroush, Rasoli Mohammad Hossein, Mohaveri Alireza
Primary Institution: Ilam University of Medical Sciences
Hypothesis
Is there a correlation between iron deficiency anemia and IgG to Helicobacter pylori in anemic children?
Conclusion
The study found a significant relationship between iron levels, IgG titers, and H. pylori infection rates, suggesting that H. pylori testing should be included in anemia evaluations.
Supporting Evidence
- 79% of the children were breastfed.
- 91% of the patients had a family history of gastrointestinal disorders.
- 62% of the children had blood group O.
- 80% of children with iron deficiency anemia had an IgG titer to H. pylori.
Takeaway
This study shows that a germ called H. pylori can make it hard for kids to absorb iron, which can lead to anemia.
Methodology
100 anemic children were analyzed using total Iron, Ferritin, TIBC, and H. pylori IgG assay, with data collected via a questionnaire and analyzed using various statistical methods.
Participant Demographics
68% girls and 32% boys, mostly from families with low monthly income and primary or secondary school literacy.
Statistical Information
P-Value
0.001
Statistical Significance
p < 0.001
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