Brunn: An open source laboratory information system for microplates with a graphical plate layout design process
2011

Brunn: An Open Source Laboratory Information System for Microplates

publication Evidence: moderate

Author Information

Author(s): Alvarsson Jonathan, Andersson Claes, Spjuth Ola, Larsson Rolf, Wikberg Jarl ES

Primary Institution: Uppsala University

Hypothesis

The study aims to develop a flexible laboratory information system for handling microplate assays.

Conclusion

Brunn is capable of handling data from microplate assays and facilitates laboratory work by allowing the reuse of plate layouts.

Supporting Evidence

  • Brunn can create dose-response curves and calculate IC50 values.
  • The system allows for the reuse of previously constructed plate layouts.
  • Brunn integrates with Bioclipse to enhance data handling capabilities.

Takeaway

Brunn is a computer program that helps scientists organize and analyze data from experiments using microplates, making their work easier and faster.

Methodology

The system was developed as a plugin for Bioclipse, featuring a point-and-click interface for designing plate layouts and managing data.

Potential Biases

Potential biases may arise from control variability and the handling of outliers.

Limitations

The current implementation is tailored for specific workflows at Uppsala University Hospital and may not be universally applicable.

Digital Object Identifier (DOI)

10.1186/1471-2105-12-179

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