Spectrum of antihypertensive therapy in South Asians at a tertiary care hospital in Pakistan
2011

Antihypertensive Therapy in South Asians

Sample size: 1191 publication Evidence: moderate

Author Information

Author(s): Almas Aysha, Rehman Iqbal Salik, Ehtamam Anabia, Khan Aamir Hameed

Primary Institution: Aga Khan University

Hypothesis

What is the frequency of patients on monotherapy and combination antihypertensive therapy in South Asians?

Conclusion

Most patients at the tertiary care center were on combination therapy, with calcium channel blockers being the most common monotherapy and beta blockers the most common in combination therapy.

Supporting Evidence

  • 85% of patients had controlled hypertension.
  • 41.2% were on monotherapy, 32.2% on two drug therapy, and 26.5% on three or more drug therapy.
  • Calcium channel blockers were the most common monotherapy.

Takeaway

This study looked at how many people in Pakistan with high blood pressure are taking one or more types of medicine to help lower it. Most people are taking more than one type of medicine.

Methodology

Cross-sectional study conducted on 1191 adults with hypertension at a tertiary care hospital over a 1.5 year period.

Potential Biases

Potential recall bias from medical records and limited external validity.

Limitations

The sample may not represent the entire population of Pakistan, and there may be recall bias and misclassification of blood pressure control.

Participant Demographics

Mean age was 62.5 years, with 45.3% males and 46.3% having diabetes.

Statistical Information

P-Value

p<0.001

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.1186/1756-0500-4-318

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication