Predictors associated with Clavien–Dindo complications in lung cancer surgery: A retrospective cohort study
2024

Predictors of Complications in Lung Cancer Surgery for Elderly Patients

Sample size: 239 publication 10 minutes Evidence: moderate

Author Information

Author(s): Saetang Mantana, Kunapaisal Thitikan, Wasinwong Wirat, Boonthum Parin, Sriyanaluk Bussarin, Nuanjun Kanjana

Primary Institution: Prince of Songkla University, Hat-Yai, Songkhla, Thailand

Hypothesis

What are the key predictors of severe postoperative complications in elderly patients undergoing lung cancer surgery?

Conclusion

Older age is associated with higher rates of postoperative complications, but comorbidities and surgical factors are significant contributors.

Supporting Evidence

  • 29.3% of patients experienced postoperative complications.
  • Older age and COPD were significant predictors of complications.
  • Conversion to open thoracotomy significantly increased complication rates.

Takeaway

Older people having lung surgery might have more problems afterward, especially if they have other health issues like COPD or if the surgery is more complicated.

Methodology

This retrospective cohort study analyzed postoperative complications in elderly patients who underwent lung cancer surgery, using logistic regression and ROC curves to identify risk factors.

Potential Biases

Potential biases due to retrospective data collection and missing records.

Limitations

The study is retrospective, which may lead to missing data, and it was conducted at a single institution, limiting generalizability.

Participant Demographics

239 elderly patients, median age 71 years, 62.9% male, with 25.7% having COPD.

Statistical Information

P-Value

0.011

Confidence Interval

95% CI: 1.02–1.15

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1371/journal.pone.0316214

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