Adjuvant Chemotherapy for Gastric Cancer After Surgery
Author Information
Author(s): Neri B, Cini G, Andreoli F, Boffi B, Francesconi D, Mazzanti R, Medi F, Mercatelli A, Romano S, Siliani L, Tarquini R, Moretti R
Primary Institution: University of Florence, Italy
Hypothesis
Does adjuvant chemotherapy improve survival rates in patients with gastric cancer after curative resection?
Conclusion
Adjuvant chemotherapy significantly improved survival rates in patients with gastric cancer after surgery compared to those who did not receive it.
Supporting Evidence
- 69 patients received adjuvant chemotherapy and 68 did not.
- 30% of treated patients were still alive after 5 years compared to 13% of controls.
- Median survival time was 31 months for treated patients and 18 months for controls.
Takeaway
This study found that giving special medicine after surgery helps more people with stomach cancer live longer.
Methodology
Patients were randomized to receive adjuvant chemotherapy or no treatment after curative resection.
Participant Demographics
Patients had gastric adenocarcinoma with positive nodes.
Statistical Information
P-Value
< 0.01
Statistical Significance
p<0.01
Digital Object Identifier (DOI)
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