New-onset gastrointestinal disorders in COVID-19 patients 3.5 years post-infection in the inner-city population in the Bronx
2024

Gastrointestinal Disorders in COVID-19 Patients 3.5 Years Later

Sample size: 35102 publication 10 minutes Evidence: high

Author Information

Author(s): Changela Sagar, Ashraf Samad, Lu Justin Y., Duong Kevin E., Henry Sonya, Wang Stephen H., Duong Tim Q.

Primary Institution: Albert Einstein College of Medicine and Montefiore Medical Center

Hypothesis

Does SARS-CoV-2 infection lead to an increased incidence of new gastrointestinal disorders up to 3.5 years post-infection?

Conclusion

COVID-19 patients are more likely to develop new gastrointestinal disorders compared to matched controls.

Supporting Evidence

  • 6.34% of COVID-19 positive patients developed new gastrointestinal disorders compared to 5.70% of controls.
  • COVID-19 patients had an adjusted hazard ratio of 1.18 for developing new gastrointestinal disorders.
  • Demographic factors such as age, sex, and race influenced the incidence of new gastrointestinal disorders.

Takeaway

People who had COVID-19 might get stomach problems even years after they got better. This study looked at a lot of patients to see how many had new stomach issues.

Methodology

This retrospective cohort study analyzed data from COVID-19 patients and matched controls to assess the incidence of new gastrointestinal disorders.

Potential Biases

Potential selection bias as only patients who returned for care were included.

Limitations

Findings are limited to patients who returned to the health system, which may not represent all COVID-19 patients.

Participant Demographics

The study included a diverse population from the Bronx, with a higher proportion of females and non-Hispanic individuals.

Statistical Information

P-Value

p<0.001

Confidence Interval

95% CI 1.12–1.25

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1038/s41598-024-83232-7

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