Impact of Advanced Platelet-Rich Fibrin on Healing After Tooth Extraction
Author Information
Author(s): Stefanescu Ada, Sufaru Irina-Georgeta, Chiscop Iulia, Lupu Fabian Cezar, Martu Cristian, Oprisan Bogdan, Earar Kamel, Chrcanovic Bruno
Primary Institution: Dunarea de Jos University, Galati, Romania
Hypothesis
Does the application of A-PRF improve healing and reduce inflammation after the extraction of mandibular third molars?
Conclusion
A-PRF enhances healing and reduces inflammation after the extraction of mandibular third molars.
Supporting Evidence
- A-PRF significantly improved probing depth and clinical attachment level compared to control sites.
- Pain and swelling were notably lower in the A-PRF group on the 7th postoperative day.
- A-PRF reduced pro-inflammatory cytokines in gingival crevicular fluid significantly more than control sites.
Takeaway
Using a special treatment called A-PRF after tooth extraction helps people heal better and feel less pain.
Methodology
This study involved 25 patients who had their impacted third molars extracted, with A-PRF applied to one side and a control on the other, measuring various healing parameters over three months.
Limitations
The study had a small sample size, limiting the generalizability of the results.
Participant Demographics
12 males (48%) and 13 females (52%), mean age 31 years.
Statistical Information
P-Value
p<0.001
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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