Rheumatoid Arthritis and Heart Failure: A Narrative Review
Author Information
Author(s): Muacevic Alexander, Adler John R, Deepika Korimerla, Moraboina Sai Lokesh, Vineetha Bodipudi, Kodali Chandana Sai, Guddeti Hema Sreelakshmi, Poladi Sanjana, Digumurthy Chandana Priya, Mellamputi Jashika
Primary Institution: Apollo Institute of Medical Sciences and Research
Hypothesis
The main objective of the study is to determine the association between rheumatoid arthritis (RA) and heart failure (HF) and the pathogenesis of HF in patients with RA.
Conclusion
The chronic inflammatory state in RA is a risk factor for the development of cardiovascular disease, and early treatment with anti-inflammatory drugs can reduce the development of complications like heart failure.
Supporting Evidence
- RA is a chronic inflammatory condition that triggers auto-immunity and increases the risk of heart disease.
- Pro-inflammatory markers in RA patients play a role in the development of heart failure.
- Early diagnosis and treatment of RA can help prevent complications like heart failure.
Takeaway
Rheumatoid arthritis can lead to heart problems, and treating it early with the right medicines can help prevent these issues.
Methodology
The review was conducted by searching the PubMed and Google Scholar databases for studies published between January 1, 1990, and May 31, 2024, focusing on the pathogenesis of HF in patients with RA.
Limitations
The review used only a few databases and there are limited studies on the definitive treatment for HF in RA.
Participant Demographics
The prevalence of RA is approximately 0.8-1.0% in Europe and the Indian subcontinent, with a female-to-male ratio of 3:1.
Statistical Information
P-Value
p=0.034
Confidence Interval
95% CI: 1.02-1.90
Digital Object Identifier (DOI)
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