Treatment of Idiopathic Parkinson's Disease with Traditional Chinese Herbal Medicine: A Randomized Placebo-Controlled Pilot Clinical Study
2011

Chinese Herbal Medicine for Parkinson's Disease

Sample size: 55 publication 10 minutes Evidence: moderate

Author Information

Author(s): Kum Wan Fung, Durairajan Siva Sundara Kumar, Bian Zhao, Xiang Man Sui, Cheung Lam, Yuen Chi Xie, Li Xia Lu, Jia Hong Wang, Yan Huang, Xian Zhang, Li Min

Primary Institution: School of Chinese Medicine, Hong Kong Baptist University

Hypothesis

Does Jia Wei Liu Jun Zi Tang improve symptoms in patients with idiopathic Parkinson's disease?

Conclusion

The study found that Jia Wei Liu Jun Zi Tang can relieve some non-motor complications of conventional therapy and improve communication abilities in patients with Parkinson's disease.

Supporting Evidence

  • JWLJZT significantly improved UPDRS IVC scores compared to placebo at 12 and 24 weeks.
  • Patients receiving JWLJZT showed significant improvement in PDQ-39 communication scores.
  • One case of mild diarrhea was reported in the treatment group.

Takeaway

This study tested a special Chinese herbal medicine on people with Parkinson's disease and found it helped them communicate better and feel less discomfort from their other treatments.

Methodology

A randomized, double-blinded, placebo-controlled trial with 55 patients receiving either herbal medicine or placebo for 24 weeks.

Potential Biases

Potential bias due to the subjective nature of some assessments and the lack of individualized treatment evaluation.

Limitations

The study was a pilot trial with a small sample size and short duration, limiting the generalizability of the findings.

Participant Demographics

Patients aged 20-80 years with idiopathic Parkinson's disease.

Statistical Information

P-Value

0.034

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1093/ecam/nep116

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication