LONG-TERM EXPOSURE TO AIR POLLUTION AND RISK OF DEMENTIA AMONG OLDER INDIVIDUALS OF A DANISH NATIONWIDE ANALYSES
2024

Air Pollution and Dementia Risk in Older Adults

Sample size: 934792 publication Evidence: high

Author Information

Author(s): So Rina, Andersen Zorana, Lim Youn-Hee, Zhang Jiawei, Tuffier Stéphane, Cole-Hunter Thomas

Primary Institution: University of Copenhagen

Hypothesis

Does long-term exposure to air pollution increase the risk of dementia among older individuals?

Conclusion

Long-term exposure to air pollution contributes to the development of dementia, particularly in vulnerable groups.

Supporting Evidence

  • 81,731 out of 934,792 subjects developed dementia.
  • Statistically significant associations were found for PM2.5, NO2, and BC with dementia incidence.
  • Hazard ratios indicated increased risk with higher pollution levels.

Takeaway

Breathing dirty air for a long time can make older people more likely to get dementia, especially if they are already sick or have less money.

Methodology

Cox proportional hazard models were used to evaluate the association between air pollution and dementia incidence.

Limitations

The study is limited to a low-exposure setting in Denmark.

Participant Demographics

Danish residents aged 60 years or older.

Statistical Information

Confidence Interval

1.12-1.16 for PM2.5, 1.22-1.28 for NO2, 1.20-1.26 for BC

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1093/geroni/igae098.1252

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