Effect of Continuous Intake of Lactobacillus salivarius WB21 on Tissues Surrounding Implants: A Double-Blind Randomized Clinical Trial
2024

Effect of Lactobacillus salivarius on Implant Health

Sample size: 23 publication Evidence: moderate

Author Information

Author(s): Taniguchi Yusuke, Suzuki Nao, Kakura Kae, Tanabe Kazunari, Ito Ryutaro, Kashiwamura Tadahiro, Fujimoto Akie, Naito Marie, Yoneda Masahiro, Hanioka Takashi, Kido Hirofumi, Dipalma Gianna

Primary Institution: Fukuoka Dental College

Hypothesis

Lactobacillus salivarius WB21 will effectively maintain the health of peri-implant tissues.

Conclusion

Continuous intake of LSWB21 may be beneficial for stabilizing peri-implant tissue.

Supporting Evidence

  • Significant improvements in mGI, mPI, and mBI were observed in the test group after 2 months.
  • Subjective symptoms such as bad breath in the test group significantly improved.
  • Changes in mGI over 2 months significantly differed between the groups.

Takeaway

Taking Lactobacillus salivarius can help keep the gums around dental implants healthy.

Methodology

A double-blind, randomized controlled trial with 23 patients divided into a test group receiving LSWB21 tablets and a control group receiving placebos.

Potential Biases

Participant allocation based on consent order may have introduced baseline differences.

Limitations

The small sample size and baseline differences in mGI between groups.

Participant Demographics

23 maintenance patients (9 men, 14 women, mean age 62.1 ± 12.3 years).

Statistical Information

P-Value

p = 0.034

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.3390/life14121532

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