Jammed Pickering Emulsion Gels
2024

Jammed Pickering Emulsion Gels

publication Evidence: high

Author Information

Author(s): J. Zhang, Y. Zheng, B. Guo, D. Sun, Y. Xiao, Z. Yang, R. Liu, J. Chen, B. Wu, P. Zhao, J. Ruan, D. A. Weitz, D. Chen

Primary Institution: Zhejiang University

Hypothesis

Can a new type of emulsion gel, called Jammed Pickering emulsion gels (JPEGs), be effectively prepared using a versatile strategy?

Conclusion

The developed JPEGs are a promising delivery platform with good biocompatibility, stability, and controlled release properties.

Supporting Evidence

  • The JPEG system is biocompatible and can be applied in various areas.
  • JPEGs are stable over a wide temperature range and against centrifugation.
  • Hydrophilic and hydrophobic drugs can be loaded in the JPEG system and released in a sustained manner.

Takeaway

Scientists created a new type of gel that can hold both water and oil together, which can be used for delivering medicine in a safe and effective way.

Methodology

The JPEGs were prepared by stabilizing water-in-oil emulsions with SiO2 nanoparticles and cross-linking them with NH2-PEG-NH2 molecules.

Limitations

JPEGs may be destroyed at very low temperatures due to ice crystallization.

Digital Object Identifier (DOI)

10.1002/advs.202409678

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