Malignant Catatonia in a 17-Year-Old Girl Due to Anti-NMDA-Receptor Encephalitis
Author Information
Author(s): Consoli Angèle, Ronen Karine, An-Gourfinkel Isabelle, Barbeau Martine, Marra Donata, Costedoat-Chalumeau Nathalie, Montefiore Delphine, Maksud Philippe, Bonnot Olivier, Didelot Adrien, Amoura Zahir, Vidailhet Marie, Cohen David
Primary Institution: Université Pierre et Marie Curie, Hôpital Pitié-Salpêtrière, AP-HP
Hypothesis
Can anti-NMDA-receptor encephalitis cause malignant catatonia in adolescents?
Conclusion
The patient improved after treatment for anti-NMDA-receptor encephalitis, with cognitive sequelae resolving within two years.
Supporting Evidence
- The patient exhibited acute mania with psychotic features and deteriorated to a catatonic state.
- She was treated with plasma exchange and immunosuppressive therapy.
- Post-cognitive sequelae resolved within a two-year follow-up.
Takeaway
A 17-year-old girl became very sick with severe mood changes and catatonia due to a brain condition called anti-NMDA-receptor encephalitis, but she got better with treatment.
Methodology
The patient was treated with immunosuppressive therapy and plasma exchange after being diagnosed with anti-NMDA-receptor encephalitis.
Limitations
The case report is based on a single patient, limiting generalizability.
Participant Demographics
The participant was a 17-year-old girl.
Digital Object Identifier (DOI)
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