Low Risk of Cervical Cancer After Negative Screening
Author Information
Author(s): van den Akker-van Marle M E, van Ballegooijen M, Habbema J D F
Primary Institution: Erasmus MC, Rotterdam, The Netherlands
Hypothesis
What is the relative risk of cervical cancer after a negative screening in the Netherlands?
Conclusion
The study found that the relative risk for cervical cancer incidence is low for several years following a negative screening using the Pap smear.
Supporting Evidence
- The study retrieved data from the Pathological National Automated Archive (PALGA) for cervical cancer cases.
- A total of 1648 invasive carcinomas were identified in the study period.
- The incidence of cervical cancer was calculated per 100,000 woman-years at risk.
Takeaway
If a woman has a negative cervical cancer screening, her chances of getting cervical cancer are low for a long time afterward.
Methodology
The study analyzed nationwide Dutch data on cervical cancer cases and linked them to screening results from a national registry.
Potential Biases
There is a risk of bias due to the identification method combining multiple women under one code.
Limitations
The identification method used may lead to an upward bias in incidence rates due to misidentification of women.
Participant Demographics
Women aged 35–64 years in the Netherlands.
Digital Object Identifier (DOI)
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