Salivary flow rate, pH, and concentrations of calcium, phosphate, and sIgA in Brazilian pregnant and non-pregnant women
2006

Salivary Changes in Pregnant and Non-Pregnant Women

Sample size: 44 publication 10 minutes Evidence: moderate

Author Information

Author(s): Rockenbach Maria I, Marinho Sandra A, Veeck Elaine B, Lindemann Laura, Shinkai Rosemary S

Primary Institution: Pontifical Catholic University of Rio Grande do Sul

Hypothesis

There are differences in salivary flow rate, pH, and biochemical composition of saliva between pregnant and non-pregnant women.

Conclusion

Pregnant women had lower pH and higher sIgA concentration than non-pregnant women, but no significant difference was found for salivary flow rates or concentrations of calcium and phosphate.

Supporting Evidence

  • Pregnant women had lower salivary pH (6.7) than non-pregnant women (7.5).
  • Pregnant women had higher sIgA levels (118.9 mg/L) compared to non-pregnant women (90.1 mg/L).
  • No significant difference was found for salivary flow rates between the two groups.
  • All values of salivary parameters were within the range of international references of normality.

Takeaway

This study looked at saliva from pregnant and non-pregnant women and found that pregnant women have different saliva characteristics, like lower pH and higher sIgA levels.

Methodology

Cross-sectional study comparing salivary variables in 22 pregnant and 22 non-pregnant women using saliva collection and biochemical assays.

Potential Biases

Potential bias due to convenience sampling and self-reported data on oral hygiene habits.

Limitations

The cross-sectional design does not allow for causal inferences.

Participant Demographics

Women aged 18 to 38 years, 22 pregnant and 22 non-pregnant.

Statistical Information

P-Value

0.026

Confidence Interval

[0.43–0.75]

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.1186/1746-160X-2-44

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