Reliability of Continuous Cardiac Output Measurement During Intra-Abdominal Hypertension
Author Information
Author(s): Gruenewald Matthias, Renner Jochen, Meybohm Patrick, Höcker Jan, Scholz Jens, Bein Berthold
Primary Institution: Department of Anaesthesiology and Intensive Care Medicine, University Hospital Schleswig-Holstein, Campus Kiel, Germany
Hypothesis
Can continuous cardiac output methods accurately detect changes during intra-abdominal hypertension and fluid loading?
Conclusion
Continuous cardiac output methods based on arterial waveform analysis need recalibration to accurately reflect changes in cardiac output during intra-abdominal hypertension.
Supporting Evidence
- All cardiac output methods showed good agreement at baseline without intra-abdominal hypertension.
- PulseCO and PCCO methods underestimated cardiac output during intra-abdominal hypertension.
- Recalibration of PCCO improved its accuracy in measuring cardiac output.
Takeaway
This study looked at how well different methods measure heart output when the belly pressure is high. It found that some methods need to be checked more often to work right.
Methodology
Ten pigs were anesthetized and monitored for cardiac output using various continuous cardiac output methods compared to a standard thermodilution technique.
Potential Biases
Potential bias due to the calibration methods and the specific conditions of the animal model.
Limitations
The study was conducted on animals, which may not directly translate to human patients.
Participant Demographics
Ten healthy German domestic pigs, weighing approximately 58 kg.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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