Factors Affecting Pulse Pressure in Hypertensive Patients
Author Information
Author(s): Kassie Maru Zewdu, Berehan Haymanot Berelie, Yilema Seyifemickael Amare, Ayele Berhanie Addis
Primary Institution: Assosa University, Assosa, Ethiopia
Hypothesis
What factors influence the longitudinal pulse pressure of hypertensive patients treated at Assosa General Hospital?
Conclusion
The study found that age, urban residence, family history of hypertension, diabetes, chronic kidney disease, smoking, and hypertension stages positively affect pulse pressure, while treatment type and follow-up time negatively affect it.
Supporting Evidence
- Age, urban residence, and family history of hypertension were positively associated with pulse pressure.
- Diabetes and chronic kidney disease also increased pulse pressure.
- Smoking status was linked to higher pulse pressure.
- Treatment with Enalapril and Nifedipine reduced pulse pressure.
- Follow-up time was negatively associated with pulse pressure.
Takeaway
This study shows that older people and those with certain health issues tend to have higher pulse pressure, but regular treatment can help lower it over time.
Methodology
A retrospective study design was conducted using data from 325 hypertensive patients, analyzed with a linear mixed model.
Potential Biases
Potential inaccuracies in medical record documentation could affect data reliability.
Limitations
The retrospective design may introduce biases, and the observational nature limits causal inferences.
Participant Demographics
51.5% female, 54.2% from urban areas, mean age 47.2 years.
Statistical Information
P-Value
<0.0001
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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