Stereotactic, single-dose irradiation of stage I non-small cell lung cancer and lung metastases
2006

Single-Dose Radiation Therapy for Lung Cancer

Sample size: 58 publication Evidence: moderate

Author Information

Author(s): Fritz Peter, Kraus Hans-Jörg, Mühlnickel Werner, Hammer Udo, Dölken Wolfram, Engel-Riedel Walburga, Chemaissani Assad, Stoelben Erich

Primary Institution: St. Marien-Krankenhaus, Department of Radiotherapy

Hypothesis

Is single-dose stereotactic irradiation an effective treatment for stage I non-small cell lung cancer and lung metastases?

Conclusion

Single-dose irradiation is an effective and safe treatment for lung tumors and may serve as a non-invasive alternative to surgery.

Supporting Evidence

  • Local control was achieved in 94% of NSCLC cases and 87% of metastases.
  • The median survival for patients with lung metastases was 26 months.
  • No serious symptomatic side effects were observed in patients.

Takeaway

Doctors used a special type of radiation treatment on patients with lung cancer and found it worked well without causing serious side effects.

Methodology

Patients underwent single-dose stereotactic body radiation therapy with a prescribed dose of 30 Gy.

Limitations

The study had a relatively small sample size and a short follow-up period for some patients.

Participant Demographics

The median age was 65 years for lung metastases and 72 years for NSCLC, with 40 men and 18 women treated.

Digital Object Identifier (DOI)

10.1186/1748-717X-1-30

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