BPhyOG: An interactive server for genome-wide inference of bacterial phylogenies based on overlapping genes
2007

BPhyOG: A Web Server for Bacterial Phylogenies

Sample size: 177 publication Evidence: moderate

Author Information

Author(s): Luo Yingqin, Fu Cong, Zhang Da-Yong, Lin Kui

Primary Institution: Beijing Normal University

Hypothesis

Can overlapping genes in bacterial genomes be used to infer phylogenetic relationships?

Conclusion

BPhyOG is a powerful tool for analyzing evolutionary relationships among bacterial genomes based on overlapping genes.

Supporting Evidence

  • BPhyOG includes 177 completely sequenced bacterial genomes.
  • The server provides access to 79,855 overlapping gene pairs.
  • Users can visualize phylogenetic trees directly on the web.

Takeaway

BPhyOG is a website that helps scientists understand how different bacteria are related by looking at shared genes.

Methodology

The server uses two tree-reconstruction methods, Neighbor Joining (NJ) and UPGMA, to infer phylogenetic trees based on overlapping genes.

Limitations

Currently, BPhyOG only includes bacterial genomes and may not accurately reflect evolutionary distances for all species.

Statistical Information

P-Value

p<0.01

Digital Object Identifier (DOI)

10.1186/1471-2105-8-266

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