Qualitative evaluation of survey questions to assess treatment preference for daily oral or long‑acting injectable antiretroviral therapy among people living with HIV
2024

Evaluating Treatment Preferences for HIV Therapy

Sample size: 30 publication Evidence: moderate

Author Information

Author(s): Garris Cindy, Kolobova Irina, Chounta Vasiliki, Díaz De Santiago Alberto, Dretler Robin, Singh Tulika, Sinclair Gary

Primary Institution: ViiV Healthcare

Hypothesis

The study aims to assess the relevance and interpretability of survey questions regarding treatment preferences for daily oral versus long-acting injectable antiretroviral therapy among people living with HIV.

Conclusion

The study confirmed that the treatment preference question and three emotional well-being questions are relevant and well understood by adults living with HIV.

Supporting Evidence

  • Participants expressed a desire for less frequent dosing and reduced emotional burden associated with daily oral ART.
  • Most participants found their current treatment regimen easy to manage despite the daily reminder of their HIV status.
  • Participants highlighted fear of disclosure and adherence anxiety as significant factors influencing their treatment preferences.

Takeaway

This study asked people living with HIV how they feel about taking their medicine every day versus getting injections every couple of months, and found that many prefer the injections because they are easier and less stressful.

Methodology

The study used a cross-sectional qualitative design involving concept confirmation and cognitive debriefing interviews with participants currently receiving HIV treatment.

Potential Biases

Participants were primarily from a well-educated US population, which may limit the generalizability of the findings.

Limitations

The study did not explore other clinical characteristics or psychosocial constructs that might influence participant feedback or HIV treatment experience.

Participant Demographics

{"mean_age":48.5,"age_range":"29-68","gender_distribution":{"male":60,"female":40},"racial_distribution":{"Black":40,"White":40,"other":20}}

Digital Object Identifier (DOI)

10.1371/journal.pone.0309588

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