Case Report of Rectal GIST Treated with Imatinib
Author Information
Author(s): Muacevic Alexander, Adler John R, Tripathi Madhumita, Purwar Roli, Sinha Richie, Singh Pooja, Pandey Manoj
Primary Institution: Institute of Medical Sciences, Banaras Hindu University, Varanasi, IND
Conclusion
Long-term treatment with imatinib for rectal GIST resulted in significant symptom relief and tumor size reduction, allowing for organ preservation.
Supporting Evidence
- The patient showed significant improvement in bowel and bladder symptoms after starting imatinib.
- MRI scans indicated a reduction in tumor size from 88x87x90 mm to 2 cm over the treatment period.
- The patient refused surgery multiple times, opting to continue with imatinib treatment.
Takeaway
A man with a rare rectal tumor was treated with a medicine called imatinib instead of surgery, and it helped shrink the tumor and made him feel better.
Methodology
The patient was treated with imatinib 400 mg daily and monitored through MRI scans over several years.
Limitations
The study is based on a single case report, limiting generalizability.
Participant Demographics
A male in his 50s with no known comorbidities.
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website