Bronchoscopy Without Sedation in Healthy Volunteers
Author Information
Author(s): Kellogg Dean III MD, Maselli Diego MD, Proud Kevin MD, Arnett Eusondia PhD, Schlesinger Larry S. MD, Peters Jay I. MD
Primary Institution: University of Texas Health at San Antonio
Hypothesis
Can bronchoscopy be performed safely and effectively without sedation in healthy volunteers?
Conclusion
The study found that bronchoscopy without sedation using topical lidocaine was well tolerated and effective for isolating human alveolar macrophages.
Supporting Evidence
- Participants reported mild discomfort with a mean value of 2.3 on a scale of 1 to 5.
- No immediate postprocedural complications occurred.
- The yield of human alveolar macrophages was satisfactory at a mean of 4.5 x 10^6 cells/mL.
Takeaway
Doctors can do a lung test without putting patients to sleep, and most people felt okay during it.
Methodology
The study involved healthy volunteers aged 18-50 who underwent unsedated bronchoscopy with topical lidocaine for airway anesthesia.
Limitations
The study did not assess the adequacy of anesthesia before bronchoscopy and did not include patients with pulmonary disease.
Participant Demographics
Participants were healthy volunteers aged 18-50, with a mean age of 27.4 years and equal sex distribution (48% female).
Digital Object Identifier (DOI)
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