Three Cases of Bacteremia Caused by Vibrio cholerae O1 in Blantyre, Malawi
Author Information
Author(s): Melita A. Gordon, Amanda L. Walsh, Sheryle R.K. Rogerson, Kingsley C. Magomero, Chipulwa E. Machili, John E. Corkill, C. Anthony Hart
Primary Institution: Queen Elizabeth Central Hospital, Blantyre, Malawi
Conclusion
This study reports three fatal cases of bacteremia caused by Vibrio cholerae O1, highlighting the clinical significance of these rare occurrences during a cholera outbreak.
Supporting Evidence
- Only four cases of invasive disease caused by V. cholerae O1 have previously been reported.
- The three cases occurred during a cholera outbreak in Blantyre, Malawi.
- Blood cultures were taken from patients with fever and shock to confirm the presence of V. cholerae O1.
Takeaway
The study describes three people who got very sick and died from a germ called Vibrio cholerae O1 during a cholera outbreak in Malawi.
Methodology
Blood cultures were taken from patients, and genomic analysis was performed to confirm the identity of the organisms as V. cholerae O1.
Limitations
Blood cultures were not routinely taken during the cholera outbreak, which may affect the true incidence of bacteremia.
Participant Demographics
The cases included two adults aged 45 and 65 years, and one neonate.
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